Welcome to the ultimate Fantasy Premier League Gameweek 4 preview for the 2025/26 season! With the transfer deadline at 11:00 BST, Saturday, September 13, 2025, FPL managers must navigate the first international break's fallout to optimize their squads. This comprehensive guide covers FPL GW4 fixtures, injury updates, best player picks, differentials, transfer trends, and captain choices to boost your rank.
FPL Gameweek 4 Fixtures 2025/26: Must-Know Matchups
Gameweek 4, headlined by the Manchester derby (Man City vs Man Utd), offers high-scoring potential and clean sheet opportunities. Below are the key FPL fixtures with FDR insights for strategic planning:
| Date | Time (BST) | Home Team | Away Team | FDR Notes |
|---|---|---|---|---|
| 13/09/2025 | 12:30 | Arsenal | Nottingham Forest | Arsenal favored (FDR 2) |
| 13/09/2025 | 15:00 | Bournemouth | Brighton | Bournemouth edge (FDR 3) |
| 13/09/2025 | 15:00 | Crystal Palace | Sunderland | Palace home strength (FDR 2) |
| 13/09/2025 | 15:00 | Everton | Aston Villa | Tough for Everton (FDR 4) |
| 13/09/2025 | 15:00 | Fulham | Leeds | Fulham favored (FDR 2) |
| 13/09/2025 | 15:00 | Newcastle | Wolves | Newcastle attack shines (FDR 3) |
| 13/09/2025 | 17:30 | West Ham | Tottenham | Goals expected (FDR 4) |
| 13/09/2025 | 20:00 | Brentford | Chelsea | Chelsea test away (FDR 3) |
| 14/09/2025 | 14:00 | Burnley | Liverpool | Liverpool dominant (FDR 2) |
| 14/09/2025 | 16:30 | Manchester City | Manchester United | High volatility (FDR 5) |
SEO Tip: Fixture swings favor Bournemouth (GW4-9), Crystal Palace (GW4-5, 10-17), and Liverpool (GW4-10). Activate your wildcard now to capitalize on these runs.
FPL Injury Updates and Team News for GW4
International breaks often disrupt squads. Monitor FPL injuries 2025/26 via press conferences for updates:
- Arsenal: Bukayo Saka (hamstring, out ~4 weeks), Kai Havertz (knee, doubtful), William Saliba (ankle, 75% chance).
- Aston Villa: Amadou Onana (hamstring, 50%), Boubacar Kamara (hamstring, 50%).
- Bournemouth: Enes Unal (ACL, doubtful), Lewis Cook (knee, possible return).
- Chelsea: Cole Palmer (groin, doubtful), Levi Colwill (ACL, season doubt), Liam Delap (hamstring, 25%).
- Crystal Palace: Ismaila Sarr (muscle, 75%), Eddie Nketiah (hamstring, October), Odsonne Edouard (Achilles, out).
- Wolves: Matheus Cunha (hamstring, out—boosts Zirkzee/Semenyo).
No major suspensions reported. Cunha's injury (200k+ sales) and Palmer's groin issue (400k+ sold) drive transfer activity.
Best FPL Player Picks for Gameweek 4
Maximize points with these FPL best picks based on xG, xFPL, and transfer trends (prices as of September 4, 2025):
FPL Differentials for Gameweek 4: Low-Ownership Stars
Boost ranks with these FPL differentials (<10% ownership):
- Bryan Mbeumo (Brentford, £7.5m): GW3 xFPL 10.8; 3 shots in box, 5 assists attempted vs Chelsea. Ownership: 8%
- Joshua Zirkzee (Man Utd, £7.0m): 7 shots GW3; derby punt. Ownership: 6%
- Eberechi Eze (Crystal Palace, £7.0m): Set-pieces, penalties vs Sunderland. Ownership: 7%
- Hugo Ekitike (Everton, £6.5m): Rising star; transfer surge. Ownership: 5%
Best FPL Captain Choices for Gameweek 4
Salah leads for safety, Haaland for upside.
💡 FPL Strategy Tips for Gameweek 4
- Wildcard: Activate for Bournemouth/Palace assets; optimal for GW4-9 fixture swings
- Transfers: Replace Cunha/Palmer; target Grealish, Joao Pedro
- Tools: Use Fixture Ticker, xFPL data for planning
- Stay Updated: Monitor press conferences for international break injuries